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Core Technology

HME-DDS

Hot-Melt Extrusion Drug Delivery System

Eco-friendly extruded
drug delivery system

It is Vignature Bio Lab's unique eco-friendly technology that allows the
development of improved new drugs with a short process time and low cost
with a single eco-friendly process without using organic solvents.

  • 01

    Simultaneous application
    of physical, chemical, and biological triplicate reactions

    Protection and stabilization of active ingredients
    Emission speed and position control are possible
    Increased absorption in the body, shielding taste/smell, ingredients
    Improved Preservation

  • 02

    Eco-friendly
    unification process

    Use the solvent X
    By-product X
    Reduce carbon emissions and energy consumption

  • 03

    Can be manufactured in
    a variety of formulations

    Pellet
    Mini-Tablet
    Gel(Ointment)
    Film

  • 04

    Applicable to a wide
    range of industries

    Medical supplies
    Health functional food
    Food
    Cosmetics

  • 05

    HME-DDS™ Optimizing process variables

    Improve the water solubility of poorly soluble ingredients and sustainability
    (Stainted-Release) and Controlled-Release are given to maximize bioavailability.

HME-DDS™ Differentiation

  • All ingredients
    can be utilized

  • Low molecular weight
    & micronization

  • Maximize active
    ingredient content

  • Diversification
    of Formulations

  • Minimize
    solvent

  • Increased skin
    permeability

  • Process
    minimization

  • Improved
    acceptance

  • Increased absorption
    rate in the body

  • Variety of
    industrialization

HME-DDS™ + 3DP

Customized, high efficiency, and innovative manufacturing of food, cosmetics,
and pharmaceuticals through the fusion of HME-DDS™ and 3DP

Simulation 1.

10 tablet
20~35% porosity
300mg

Simulation 2.

50 tablet
5~15% porosity
550mg

Printing